Diazepam is a benzodiazepine that exerts anxiolytic, sedative, muscle- relaxant Diazepam is N-demethylated by CYP3A4 and 2C19 to the active metabolite. Apr 15, - The metabolism and excretion of diazepam is somewhat convoluted; however, with a basic understanding of the excretion toxicology, providers. Jump to Metabolism - Metabolism Diazepam is primarily metabolized by hepatic species responsible for diazepam metabolism (Perucca et al., ) Absorption by route of · Pharmacodynamics · Interactions · Main adverse effects.
Apr 30, - Results of a controlled trial do not support the superiority of lorazepam over diazepam as a first-line agent for pediatric status epilepticus. Jan 3, - (the diluent used in parenteral formulations of diazepam and lorazepam). Although rare, this may result in hypotension, cardiac dysrhythmias. Find patient medical information for Diazepam Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
A list of drugs that interact with Venlafaxine. Both venlafaxine and diazepam can have CNS depressant effects, which might affect the ability to perform skilled. Venlafaxine, sold under the brand name Effexor among others, is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. This means. As with all drugs, the potential for interaction by a variety of mechanisms is a Venlafaxine had no effect on the pharmacokinetics of diazepam or its active.