Tag Archives: depression

Oral Allopregnanolone Analogue for Postpartum Depression Treatment

In 2015, we first reported on SAGE-547 (SAGE Therapeutics), a new medication for the treatment of postpartum depression (PPD).  SAGE-547, now called brexanolone, is a neurosteroid, an analogue of allopregnanolone and an allosteric modulator of GABAA receptors.  Since that time, Sage Therapeutics has conducted three randomized controlled trials, enrolling a total of 247 women diagnosed… Read More »

Depression in New Moms Adversely Affects the Health of Babies and Other Family Members

Maternal depression experienced by half of expectant and new mothers go undiagnosed and untreated, which can lead to major long-term health problems both for parents and for their infants. In an effort to prevent such complications, a new report released by the American Academy of Pediatrics (AAP) is once again urging doctors to screen mothers… Read More »

Transcranial Magnetic Brain Stimulation to Treat Depression and OCD: Interview with Stanford’s Dr. Nolan Williams

Chances are, someone you know has been affected by mental health problems. With an estimated world-wide burden of 300 million people, depression can be a severely debilitating condition. In fact, in the past year alone, more than 16 million adults in the US have experienced a major depressive episode. While many of those who seek help… Read More »